Instrumentation Facilities

FT-IR

The Fourier Transform Infrared (FTIR) spectrometer can be used in various areas like organic synthesis, polymer science, material science, etc. As a molecule only absorbs selected frequencies, this technique can be considered a fingerprint for it. Here, the absorption only occurs if the frequency of the spectra matches the natural vibrational frequencies of the molecule. Bruker ALPHA II FT-IR spectrometer is a compact, modular instrument suitable for routine infrared analysis across diverse sample types. The system enables streamlined operation and data acquisition, which can be very fruitful for academic and research purposes.

UV-Visible

UV-Visible spectroscopy is a widely used analytical technique for characterizing the electronic transitions of molecules, particularly in the context of conjugated systems and chromophores. It operates in the ultraviolet and visible regions of the electromagnetic spectrum, typically between 200–800 nm, and provides insights into molecular structure, concentration, and purity. The Ultraviolet-visible (UV-Vis) spectrum is generally recorded as a plot of absorbance versus wavelength. With halogen and deuterium lamps ensuring low noise and stable baselines, the UV-1900i is well-suited for both routine and advanced spectroscopic applications in research and quality control.

Fluorescence

Fluorescence is the emission of light by a substance that has absorbed electromagnetic radiation, typically at a shorter wavelength, and re-emits it at a longer wavelength. The Hitachi F-4700 Fluorescence Spectrophotometer is engineered to capture fluorescence phenomena with exceptional precision. This high-performance instrument enables researchers to detect even trace levels of fluorescent compounds, making it indispensable in fields like biochemistry, pharmacology, and environmental science.

Zetasizer

DLS

Dynamic Light Scattering (DLS) is a technique used to measure the size of particles or molecules in a liquid suspension, typically in the nanometer to micrometer range. It works by shining a laser on a colloidal or nanoparticle suspension and analyzing the fluctuations in scattered light intensity caused by the Brownian motion of particles. These fluctuations are used to calculate the diffusion coefficient, from which the hydrodynamic diameter of particles is determined using the Stokes–Einstein equation. DLS is widely used for nanoparticles, emulsions, proteins, and other colloids. It is quick, non-invasive, and requires only a small amount of sample. It also provides a Polydispersity Index (PDI), indicating how uniform the particle sizes are in a sample.

Zeta Potential

It is the electrical potential at the slipping plane of a particle suspended in a liquid. It reflects the net surface charge of the particle and how strongly it attracts or repels other particles. A sample is considered stable if the zeta potential falls beyond |± 30 mV|.

Lyophilizer

The lyophilizer, also known as a freeze dryer, is used to dehydrate materials through a process known as lyophilization. Lyophilizers are essential in pharmaceuticals, biotechnology, and food science for stabilizing heat-sensitive compounds like proteins, vaccines, and enzymes without compromising their structural integrity. By freezing the material and then reducing pressure to allow sublimation, it avoids the damaging effects of heat and oxidation.

Rotary Evaporator

A rotary evaporator, (rotovap) is a laboratory device designed for the efficient and gentle removal of solvents from samples through evaporation under reduced pressure. Widely used in organic chemistry, pharmaceuticals, and natural product extraction, the rotovap enables concentration, purification, and solvent recycling with high precision. It operates by rotating a sample flask in a heated water bath while applying vacuum, which lowers the boiling point of the solvent and accelerates evaporation without degrading heat-sensitive compounds.

Muffle Furnace

The Muffle Furnace (Model BTI-36) from Bio Technics India is designed for high-temperature applications requiring controlled heating up to 1000?°C. It is suitable for tasks such as ashing, sintering, and thermal decomposition in research and teaching laboratories. The furnace features a robust insulated chamber that ensures uniform temperature distribution and energy efficiency.

Computational Studies

The lab is equipped with 3 high performance workstations for computational studies tailored for advanced molecular modelling, quantum chemistry and simulation studies. Each system has a configuration of Intel Xeon 24 core, 48 thread CPU with 128GB RAM and Nvidia RTX A4500 GPU with 16 GB of VRAM.